Premature ovarian failure

What is premature ovarian failure?

Premature ovarian failure (POF), also known as primary ovarian insufficiency, is a disorder that causes menopause to occur earlier than normal in a woman's life, typically before age 40. This happens because the ovaries stop functioning properly and oocyte depletion occurs earlier than expected.

Some key facts about POF:

• It affects around 1% of women under the age of 40.


• The cause is often unknown, but sometimes it may be due to genetics, autoimmune disorders, chemotherapy treatment, or infections.


• Main symptoms are irregular periods, reduced fertility, hot flashes, vaginal dryness, and mood changes typical of menopause.


• Diagnosis is usually made by blood tests showing high follicle-stimulating hormone (FSH) levels.


• Treatment focuses on managing symptoms. Hormone replacement therapy helps supplement estrogen and progesterone levels.

While coping with POF can be difficult emotionally and physically, women can still live full and healthy lives. The key is being informed and proactive.

In summary, premature ovarian failure is due to ovaries stopping normal functioning before age 40, causing an early menopause. Though challenging, women can manage POF by monitoring health, supplementing hormones if needed, and getting support. The future is still bright. What specific questions do you have about POF? I'm happy to help provide more information or resources if useful!